Method for the manufacture of a pharmaceutical form of...

Details Method for the manufacture of a pharmaceutical form of... Method for the manufacture of a pharmaceutical form of...

A - Human Necessities

61

K

A61K 31/245 (2006.01)

Patent

CA 2632890

The invention relates to a method for the manufacture of a pharmaceutical form of oseltamivir phosphate, characterized in that it comprises the following steps: a) compacting followed by screening of an oseltamivir phosphate powder; b) dry-mixing, with known excipients, of the product obtained at the end of the previous step, followed by screening. Application to an industrial production suitable for a crisis situation, such as a pandemic.

L'invention concerne un procédé de fabrication d'une forme pharmaceutique de phosphate d'oseltamivir, caractérisé en ce qu'il comprend les étapes suivantes : a) compactage suivi d'un calibrage d'une poudre de phosphate d'oseltamivir ; b) mélange à sec avec des excipients connus du produit obtenu à l'issue de l'étape précédente, suivi d'un calibrage. Application à une production industrielle adaptée à une situation de crise, telle qu'une pandémie.

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