Method for the performance of a mutagenicity test

Details Method for the performance of a mutagenicity test Method for the performance of a mutagenicity test

C - Chemistry, Metallurgy

12

Q

73/55, 150/16.1

C12Q 1/02 (2006.01) G01N 21/59 (2006.01) G01N 21/84 (2006.01) G01N 33/50 (2006.01)

Patent

CA 1204373

Abstract of the Disclosure Method for the performance of a mutagenicity test so that a cell population is subjected to a mutagen. As a result of this, a part of the population mutates, whereat the originally uniform cell population is differentiated into sub-populations. The variation of turbidity caused by the increase in the density of the differentiated cell populations is measured as a change in optical density by means of a photometer measuring vertically at a certain wavelength, and the quantity of cells in the sub-populations is determined as optical density. The absorbance values are measured in accordance with a pre-programmed time share system and a growth curve is formed out of the values as a function of time.

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