Method for the preparation of 2-alkylindanes

Details Method for the preparation of 2-alkylindanes Method for the preparation of 2-alkylindanes

C - Chemistry, Metallurgy

07

C

260/680.8

C07C 1/20 (2006.01) C07C 1/22 (2006.01) C07C 13/465 (2006.01) C07C 45/66 (2006.01) C07C 45/75 (2006.01) C07C 49/82 (2006.01)

Patent

CA 1062286

ABSTRACT OF THE DISCLOSURE The present invention relates to a method for the preparation of 2-alkyl indane. This method is characterised in that : a) fromaldehyde or a precursor of formaldehyde is condensed with an aromatic ketone of formula : Image in which R is an alkyl or cycloalkyl group in a basic medium in a polar organic solvent, with a view to obtaining a ketol, b) the ketol thus obtained is cyclized in a strong acid medium to give an indanone and c) the indanone is reduced to obtain the desired product. - 1 -

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