Method for the preparation of a scintillographic agent

C - Chemistry – Metallurgy – 07 – F

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260/428.1, 260/5

C07F 13/00 (2006.01) A61K 51/04 (2006.01)

Patent

CA 1161455

ABSTRACT OF THE DISCLOSURE The invention is a method of preparing an N-(2,4-dimethylphenyl- carbamoylmethyl)-iminodiacetic acid which comprises reacting an .omega.-chloro-2,4- dimethylacetanilide with a sodium salt of iminodiacetic acid. The N-(2,4- dimethylphenyl-carbamoylmethyl)-iminodiacetic acid can be chelated with technetium 99m Tc, to form a scintillographic agent which displays improved durability when compared with known scintillographic agents.

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