Method for the preparation of new oligoclonal antibodies

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 16/18 (2006.01)

Patent

CA 2700293

A process is provided for the preparation of antibodies or fragments thereof using a prokaryotic host cell containing DNA sequences encoding for said antibodies of fragments thereof, wherein said DNA sequence is derived from a coronary plaque sample. Compositions containing said antibodies are also provided. Ligands to said antibodies and compositions containing said ligands are also described.

La présente invention concerne un procédé de préparation d'anticorps ou de fragments de ceux-ci utilisant une cellule hôte procaryotique qui contient des séquences d'ADN codant pour lesdits anticorps ou fragments de ceux-ci. Lesdites séquences d'ADN sont dérivées d'un échantillon de plaque coronarienne. L'invention concerne également des compositions contenant lesdits anticorps. Enfin, l'invention concerne des ligands pour lesdits anticorps et des compositions contenant lesdits ligands.

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