Method for the preparation of pyridoxylated hemoglobin

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/805 (2006.01) A61K 35/18 (2006.01) A61K 38/42 (2006.01) C07K 1/113 (2006.01)

Patent

CA 2079006

2079006 9116352 PCTABS00007 A pyridoxylated hemoglobin is prepared in a one-step, one-container process from red blood cells or essentially stroma-free hemoglobin by suspending the cells or hemoglobin in an aqueous medium, adding a chemical reducing agent and a pyridoxylating agent, and heating the reaction mixture obtained at a certain temperature for a certain time, while maintaining reducing conditions in the reaction medium.

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