Method for the prevention of gastro-intestinal ulcer caused...

Details Method for the prevention of gastro-intestinal ulcer caused... Method for the prevention of gastro-intestinal ulcer caused...

A - Human Necessities

61

K

167/218

A61K 31/505 (2006.01)

Patent

CA 1062615

METHOD FOR THE PREVENTION OF GASTRO-INTESTINAL ULCER CAUSED BY A NON-STEROIDAL ANTI-INFLAMMATORY AGENT ABSTRACT OF THE DISCLOSURE A method for preventing gastro-intestinal ulcer caused by a non-steroidal anti-inflammatory agent, which comprises administering an effective amount of a quinazolinone of the formula, Image wherein R1 is C1 3 alkyl, cyclopropylmethyl or 2,2,2- trifluoroethyl, R2 is halogen, C1-3 alkyl or C1-3 alkoxy, and R3 is phenyl or thienyl, or a non-toxic pharmaceutically acceptable salt thereof in combination with a pharmaceutically effective amount of the non- steroidal anti-inflammatory agent.

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