A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/24 (2006.01) A61K 31/196 (2006.01)
Patent
CA 2361581
This invention provides a method for the prevention or reduction of cardiovascular events associated with coronary intervention in a mammal, particularly a human, which comprises administering to the subject N-(3',4'- dimethoxycinnamoyl)anthranilic acid (N-5') or a pharmaceutically acceptable salt thereof in a daily dose of from greater than 300 mg to about 1,200 mg for a treatment period of up to 89 days in association with coronary intervention.
L'invention concerne une méthode de prévention ou réduction d'incidents cardio-vasculaires associés à une intervention coronarienne, chez un mammifère, notamment chez l'homme, cette méthode consistant à administrer à ce sujet un acide N-(3',4'-diméthoxycinnamoyl)anthranilique (N-5') ou un sel de celui-ci, acceptable sur le plan pharmacologique, en dose quotidienne comprise entre une quantité supérieure à 300 mg et environ 1200 mg, pendant une période pouvant couvrir jusqu'à 89 jours, en relation avec l'intervention coronarienne.
Granett Jeffrey R.
Shusterman Neil H.
U'prichard David C.
Gowling Lafleur Henderson Llp
Smithkline Beecham Corporation
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