Method for the production of a tamper-proof form of...

Details Method for the production of a tamper-proof form of... Method for the production of a tamper-proof form of...

A - Human Necessities

61

K

A61K 9/20 (2006.01) A61K 31/135 (2006.01)

Patent

CA 2595979

The invention relates to a method for producing a tamper-proof form of administration containing at least one synthetic or natural polymer (C) having a minimum breaking strength of 500 N in addition to one or several tamper- prone agents and optional physiologically acceptable adjuvants. A solvent for the polymer (C) is added to the formulation mixture at such amounts that the formulation mixture is at least evenly moistened, the at least moistened mass is optionally subdivided into partial masses, is dried, and is shaped into the form of administration.

Procédé de production d'une forme galénique protégée contre une utilisation abusive, qui contient, outre un ou plusieurs principes actifs à potentiel d'utilisation abusive et éventuellement des additifs physiologiquement compatibles, au moins un polymère synthétique ou naturel (C) ayant une résistance à la rupture d'au moins 500 N. Ledit mélange est mis en réaction avec un solvant pour le polymère (C) au moins dans des quantités telles qu'il est humidifié de manière homogène, et la masse humidifiée est éventuellement dosée et séchée, ce qui permet d'obtenir une forme galénique destinée à être administrée.

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