C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 317/44 (2006.01) A61K 31/165 (2006.01) A61P 25/00 (2006.01) C07C 315/06 (2006.01)
Patent
CA 2510096
The invention relates to a method for the production of crystalline forms of optical enantiomers of modafinil, comprising the following steps:i) one of the optical enantiomers of modafinil is dissolved in a solvent other than ethanol; ii) the enantiomer of modafinil is crystallized; iii) the crystalline form of the enantiomer of modafinil thus obtained is recovered. The invention also relates to a method for the production of optical enantiomers of modafinil.
L'invention a pour objet un procédé de préparation de formes cristallines des énantiomères optiques du modafinil, comprenant les étapes consistant à :i) dissoudre l'un des énantiomères optiques du modafinil dans un solvant autre que l'éthanol ;ii) cristalliser l'énantiomère du modafinil ;iii) récupérer la forme cristalline de l'énantiomère du modafinil ainsi obtenue.L'invention vise également un procédé de préparation des énantiomères optiques du modafinil.
Besselievre Christine
Coquerel Gerard
Courvoisier Laurent
Graf Stephanie
Leproust Pierre
Cephalon France
Organisation de Synthese Mondiale Orsymonde
Robic
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