Method for the production of glycerol by recombinant organisms

Details Method for the production of glycerol by recombinant organisms Method for the production of glycerol by recombinant organisms

C - Chemistry, Metallurgy

12

N

C12N 1/21 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 9/04 (2006.01) C12N 9/16 (2006.01) C12N 15/53 (2006.01) C12N 15/55 (2006.01) C12N 15/63 (2006.01) C12P 7/20 (2006.01)

Patent

CA 2311601

Recombinant organisms are provided comprising genes encoding a glycerol-3- phosphate dehydrogenase and/or a glyc-erol-3-phosphatase activity useful for the production of glycerol from a variety of carbon substrates. The organisms further contain disruptions in the endogenous genes encoding proteins having glycerol kinase and glycerol dehydrogenase activities.

L'invention porte sur des organismes de recombinaison comportant des gènes codant pour des protéines à activité de glycérol-3-phosphate déshydrogénase et/ou de glycérol-3-phosphatase, et servant à la production de glycérol à partir de différents substrats de carbone. Lesdits organismes comportent de plus des délétions de gènes endogènes codant pour des protéines à activité de glycérol kinase et de déshydrogénase.

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