Method for the production of nuclear substituted...

Details Method for the production of nuclear substituted... Method for the production of nuclear substituted...

C - Chemistry, Metallurgy

07

D

260/512.3

C07D 295/027 (2006.01)

Patent

CA 1189090

ABSTRACT OF THE DISCLOSURE The present invention provides an improved method for producing a nuclear substituted cinnamoylanthranilic acid compound. Illustrative of the process is the reaction of 3,4- dimethoxybenzaldehyde with 2-carboxymalonanilic acid in an inert solvent medium in the presence of piperidine to provide an intermediate salt precipitate, and the salt is treated with an acidic reagent to yield N-(3,4-dimethoxy- cinnamoyl)anthranilic acid product. -17-

410210

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