Method for the production of proteins by means of inducible...

Details Method for the production of proteins by means of inducible... Method for the production of proteins by means of inducible...

C - Chemistry, Metallurgy

12

N

195/1.18, 195/1.

C12N 15/85 (2006.01) A01K 67/027 (2006.01) C07K 14/61 (2006.01) C12N 5/10 (2006.01) C12N 15/11 (2006.01) C12N 15/87 (2006.01)

Patent

CA 1319631

ABSTRACT In the production of proteins of biological interest by means of a stress inducible gene expression unit/eukaryotic host cell system, the transformed cell lines are multiplicated by tumour growing in immunodefficient warm-blooded animals, after which the multiplicated cells are cultured in vitro and subjected to stress, whereby expression occurs in high yield. In vivo multiplication rates of 105-106 the innoculated quan- tity/2 weeks are reported without any loss of the latent inducible expression capacity.

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