C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/04 (2006.01) C12N 5/14 (2006.01) C12P 7/22 (2006.01)
Patent
CA 2486588
The invention relates to a method for the production of resveratrol in cell cultures. The inventive method consists in: incubating a culture of cells which produce resveratrol naturally, in suspension, in the presence of randomly-methylated .beta.-cyclodextrin (RMBCD) with a degree of substitution of between 11 and 13 under conditions that allow resveratrol synthesis and the excretion of same into the culture medium; and, if desired, isolating the resveratrol produced from said culture medium. The resveratrol can be used in the production of pharmaceutical or nutraceutical products.
Ce procédé consiste à incuber une culture de cellules productrices de resvératrol naturellement, en suspension, en présence d'une .beta.-cyclodextrine methylée aléatoirement (BCDMA) ayant un degré de substitution compris entre 11 et 13 dans des conditions qui permettent la synthèse de resvératol et son excrétion dans le milieu de culture, et à isoler, éventuellement, le resvératol produit du milieu de culture. Le resvératol peut être utilisé dans la préparation de produits pharmaceutiques ou nutraceutiques.
Bru Martinez Roque
Pedreno Garcia Maria de Los Angeles
Marks & Clerk
Universidad de Alicante
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