Method for the production of solid formulations of sodium...

Details Method for the production of solid formulations of sodium... Method for the production of solid formulations of sodium...

A - Human Necessities

61

K

A61K 31/19 (2006.01) C07C 51/09 (2006.01)

Patent

CA 2447417

Solid formulations of sodium 3-hydroxy-3-methylbutyrate are produced by the hydrolysis of 4,4-dimethyl-2-oxe- tanone with aqueous sodium hydroxide to give a solution of sodium 3-hydroxy-3-methylbutyrate and the solution obtained thus is absorbed onto synthetic silicic acid. Said formulations are lightly hygroscopic and easily handled.

Procédé de production de compositions solides de 3-hydroxy-3-méthylbutyrate de sodium qui consiste à hydrolyser de la 4,4-diméthyloxétan-2-one avec de l'hydroxyde de sodium aqueux pour obtenir une solution de 3-hydroxy-3-méthylbutyrate de sodium, la solution ainsi obtenue étant absorbée par de l'acide silicique synthétique. Lesdites compositions sont peu hygroscopiques et peuvent être maniées facilement.

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