Method for the production of thrombin

Details Method for the production of thrombin Method for the production of thrombin

C - Chemistry, Metallurgy

12

N

C12N 9/74 (2006.01)

Patent

CA 2227883

A method for the preparation of thrombin from a prothrombin-containing material is characterised in that the prothrombin-containing material is an activated prothrombin complex concentrate (ActPCC) fraction, which is contacted with divalent cations to convert the prothrombin to thrombin.

Cette invention concerne un procédé de préparation de thrombine à partir d'une matière contenant de la prothrombine. La matière contenant de la prothrombine consiste en une fraction d'un concentré de complexe de prothrombine activé (ActPCC), laquelle est mise en contact avec des cations divalents afin de transformer la prothrombine en thrombine.

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