Method for the production of trans- or...

C - Chemistry – Metallurgy – 07 – F

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C07F 15/00 (2006.01) A61K 31/28 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2565096

The invention relates to a method for the preparation of trans- or cis-diammoniumdichlorodihydroxoplatinum(IV) and derivatives thereof. What is suggested is reacting trans-or cis-diammoniumdichloroplatinum(II) with a solution com-prising >30% peroxide at temperatures below 30°C and dis-solving the product thus obtained in a mineral acid and subsequently precipitating with an alkaline solution.

L'invention concerne un procédé pour produire du trans- ou cis-diammoniumdichlorodihydroxoplatine (IV) et leurs dérivés. Ce procédé consiste à faire réagir du trans- ou cis-diammoniumdichloroplatine (II) avec une solution contenant plus de 30 % de peroxyde, à des températures inférieures à 30 ·C; à dissoudre le produit ainsi obtenu avec un acide minéral, et enfin à provoquer la précipitation dudit produit avec une solution alcaline.

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