A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/57 (2006.01) C07K 1/22 (2006.01) C07K 14/81 (2006.01) C12P 21/02 (2006.01)
Patent
CA 2631524
The invention relates to methods for the isolation of AAT from solutions containing albumin and AAT using at least two separate metal chelate chromatography steps. The product may be further purified and/or subjected to one or more virus inactivation or reduction steps. The isolated AAT may then be formulated for pharmaceutical use.
L~invention concerne des procédés d~isolation d~AAT à partir de solutions qui contiennent de l~albumine et de l~AAT en utilisant au moins deux étapes séparées de chromatographie à chélates métalliques. Le produit peut être davantage purifié et/ou soumis à une ou plusieurs étapes d~inactivation ou de réduction du virus. L~AAT isolée peut alors être formulée pour une utilisation pharmaceutique.
Dalton Joan
Kumpalume Peter
Podmore Adrian
Bio Products Laboratory Limited
Fetherstonhaugh & Co.
Nhs Blood And Transplant
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