C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/81 (2006.01)
Patent
CA 2614838
The present invention relates to a method for the purification of alpha-1 proteinase inhibitor (a1PI) from protein fractions. More specifically, the invention relates to an improved method for the purification of alpha-1 proteinase inhibitor (a1PI), wherein the yield of a1PI can be increased by thawing the starting material and incubating it for several hours before subjecting it to a washing step.
La présente invention concerne un procédé destiné à la purification d'un inhibiteur de l'alpha-1 protéinase (a1PI) à partir de fractions protéiques. L'invention concerne plus précisément un procédé amélioré destiné à la purification d'un inhibiteur de l'alpha-1 protéinase, dans lequel le rendement d'a1PI peut être augmenté par décongélation du produit de départ et incubation pendant plusieurs heures avant une étape de lavage.
Brachtl Gerald
Matthiessen Peter
Schwarz Hans-Peter
Turecek Peter
Baxter Healthcare S.a.
Baxter International Inc.
Sim & Mcburney
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