Method for the purification of antibodies

Details Method for the purification of antibodies Method for the purification of antibodies

C - Chemistry, Metallurgy

07

K

C07K 16/00 (2006.01) C07K 1/18 (2006.01) G01N 30/34 (2006.01)

Patent

CA 2607375

A method for the purification of immunoglobulins by ion exchange chromatography is described. The chromatographic method uses a weak ion exchange resin and a single step elution process for the purification of an immunoglobulin. Additionally a method for the determination of the salt concentration for the single step elution of an immunoglobulin from an ion exchange resin is described.

L'invention concerne une méthode de purification d'immunoglobulines par chromatographie d'échange d'ions. La méthode chromatographique fait appel à une résine échangeuse d'ions faible et à un procédé d'élution en une étape pour la purification d'une immunoglobuline. L'invention concerne en outre une méthode destinée à déterminer la concentration en sel pour l'élution en une étape d'une immunoglobuline à partir d'une résine échangeuse d'ions.

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