Method for the purification of interferon

Details Method for the purification of interferon Method for the purification of interferon

A - Human Necessities

61

K

167/103.1

A61K 39/42 (2006.01) C07K 14/565 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1166959

ABSTRACT OF THE DISCLOSURE Human fibroblast interferon may be purified to a high degree by using a simple two-step purification method comprising (a) subjecting an aqueous interferon solution to chromatography on porous glass beads, and (b) subjecting the resulting aqueous interferon solution to chromatography on immobolized zinc chelate. Overall recoveries of about 45-76% of the initial interferon activity may be reached and the end product will be free of any skin reactive agent.

363070

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