Method for the purification of therapeutically active...

Details Method for the purification of therapeutically active... Method for the purification of therapeutically active...

C - Chemistry, Metallurgy

12

N

195/78, 530/15.0

C12N 15/18 (2006.01) A61K 38/18 (2006.01) C07K 14/50 (2006.01)

Patent

CA 2020720

7370P/5411A 17878 TITLE OF THE INVENTION A METHOD FOR THE PURIFICATION OF THERAPEUTICALLY ACTIVE RECOMBINANT ACIDIC FIBROBLAST GROWTH FACTOR ABSTRACT OF THE DISCLOSURE An improved method for the purification of acidic fibroblast growth factor (aFGF) is disclosed. The methodology includes extraction, ion exchange chromatography, affinity chromatography, reversed phase-HPLC, solvent exchange solubilization and/or hydrophobic interaction chromatography. The method results in an increase in mitogenic potency, an increase in solubility and allows the separation of recombinant aFGF from truncated forms of recombinant aFGF.

Affiliated with

Also associated with

Rating

Method for the purification of therapeutically active... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for the purification of therapeutically active..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for the purification of therapeutically active... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1784783