Method for the recombinant production of 1,3-propanediol

Details Method for the recombinant production of 1,3-propanediol Method for the recombinant production of 1,3-propanediol

C - Chemistry, Metallurgy

12

N

C12N 15/53 (2006.01) C12N 9/04 (2006.01) C12N 9/16 (2006.01) C12N 9/88 (2006.01) C12N 15/52 (2006.01) C12N 15/55 (2006.01) C12N 15/60 (2006.01) C12P 7/18 (2006.01)

Patent

CA 2270906

The present invention provides an improved method for the production of 1,3- propanediol from a variety of carbon sources is an organism comprising DNA encoding protein X of a dehydratase or protein X in combination with at least one of protein 1, protein 2 and protein 3. The protein X may be isolated from a diol dehydratase or a glycerol dehydratase. The present invention also provides host cells comprising protein X that are capable of increased production of 1,3-propanediol.

L'invention porte sur un procédé amélioré de production de 1,3-propanédiol à partir de diverses sources de carbone dans un organisme comportant l'ADN codant pour la protéine X d'une déshydratase, ou la protéine X combinée à au moins une protéine 1, ou une protéine 2, ou une protéine 3. La protéine X peut être isolée dans une dioldéshydratase ou une glycéroldéshydratase. L'invention porte également sur des cellules hôtes comprenant la protéine X, capables d'assurer une production accrue de 1,3-propanédiol.

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