C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2427066
The invention relates to novel peptides taken from human blood, hBD-5 (human beta-defensin 5), hBD-6, hBD-7, hBD-8, hBD-10, hBD-11, hBD-12, hBD-13, hBD-14, hBD-15, hBD-16, hBD-17, hBD-18, hBD-19, hBD-20, hBD-22, hBD-23, hBD-24, hBD- 25, hBD-26, hBD-27, hBD-28, hBD-29, hBD-30, hBD-31 and hBD-32 and the derivatives thereof, the structure of the same having been elucidated so that they can be used therapeutically, diagnostically and commercially as medicaments. Said peptides can be produced by means of biotechnological, recombinant methods and chemical synthesis, and can be proteolytically derived from corresponding precursor proteins.
Nouveaux peptides tirés du sang humain hBD-5 (bêta-défensine-5 humaine), hBD-6, hBD-7, hBD-8, hBD-10, hBD-11, hBD-12, hBD-13, hBD-14, hBD-15, hBD-16, hBD-17, hBD-18, hBD-19, hBD-20, hBD-22, hBD-23, hBD-24, hBD-25, hBD-26, hBD-27, hBD-28, hBD-29, hBD-30, hBD-31 et hBD-32 et leurs dérivés, dont la structure a pu être établie et qui sont destinés à être utilisés à titre thérapeutique, diagnostique et commercial en tant que médicaments. Lesdits peptides peuvent être fabriqués à l'aide de procédés biotechnologiques de recombinaison, de la synthèse chimique ainsi que de manière protéolytique à partir de protéines précurseurs correspondantes.
Adermann Knut
Conejo-Garcia Jose-Ramon
Forssmann Wolf-Georg
Ipf Pharmaceuticals Gmbh
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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