Method for the separation of intermediates which may be used...

C - Chemistry – Metallurgy – 07 – D

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C07D 307/87 (2006.01) A61K 31/343 (2006.01) C07B 57/00 (2006.01) C07C 253/30 (2006.01) C07C 253/34 (2006.01) C07C 255/34 (2006.01) C07C 255/53 (2006.01)

Patent

CA 2495118

The present invention relates to a novel method for the preparation of diol intermediates having the formula (II) and/or the opposite enantiomer of an acylated diol having the formula (IV) useful for the preparation of escitalopram involving selective enzymatic acylation or deacylation.

L'invention porte sur un nouveau procédé de préparation de produits intermédiaires de diol représentés par la formule (II) et/ou de l'énantiomère opposé d'un diol acylé représenté par la formule (IV), utiles dans la préparation d'escitalopram comprenant l'acylation ou la désacylation enzymatique sélective.

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