C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
195/1.12
C12N 15/89 (2006.01) C12N 15/10 (2006.01) C12N 15/90 (2006.01)
Patent
CA 2011784
A b s t r a c t For the targetted change of a gene within the genome of intact mammalian cells by homologous recombination a DNA sequence, which is homologous to the gene to be changed but, however, differs by at least one nucleotide from its sequence as a result of mutation, deletion, or insertion, is introduced into appropriate cells by microinjection and cells are isolated in which the resultant change can be detected.
Gruss Peter
Zimmer Andreas
Gruss Peter
Max Planck Gesellschaft Zur Forderung Der Wissenschaften E.v.
Max-Planch-Gesellschaf Fur Forderung Wissenschaften E.v.
Swabey Ogilvy Renault
Zimmer Andreas
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