Method for the treatment of cardiac and of vascular...

A - Human Necessities – 61 – K

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167/103.05

A61K 38/05 (2006.01) A61K 38/55 (2006.01)

Patent

CA 2023089

The invention relates to a method for the treatment of cardiac and of vascular hypertrophy and hyperplasia by administration of angiotensin converting enzyme inhibit- ors. Administration of compounds of the formula I (see formula I) in which n is 1 or 2, R, R1, R2 and R3 are identical or different and each is hydrogen or an organic radical, and R4 and R5 form, together with the atoms carrying them, a mono-, bi- or tricyclic heterocyclic ring system, is preferred. The invention additionally relates to angio- tensin converting enzyme inhibitors and to agents con- taining these for administration for the treatment of the abovementioned diseases.

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