Method for the treatment of gastroesophageal reflux disease

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/00 (2006.01) A61K 31/415 (2006.01) A61K 31/425 (2006.01) A61K 31/44 (2006.01) A61K 39/00 (2006.01) A61K 39/385 (2006.01)

Patent

CA 2332774

A method for the treatment of gastroesophageal reflux disease comprising a combination of active immunization with an anti-gastrin immunogenic composition with an antagonist which blocks or inhibits the gastric acid pump activity; or alternatively administering purified anti-gastrin antibodies with a H2 antagonist or proton pump inhibitor of the gastric acid producing enzyme system.

L'invention concerne une méthode de traitement de reflux gastro-oesophagien pathologique, qui comporte une combinaison d'immunisation active mise en oeuvre à l'aide d'une composition immunogène antigastrine et d'un antagoniste qui bloque ou inhibe l'activité de la pompe d'acide gastrique; ou dans un autre mode de réalisation, par l'administration d'anticorps antigastrine purifiés et d'un antagoniste de H¿2? ou d'un inhibiteur de la pompe de protons du système d'enzymes produisant l'acide gastrique.

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