A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/485 (2006.01) A61K 31/00 (2006.01) A61K 31/135 (2006.01) A61K 31/167 (2006.01) A61K 45/06 (2006.01) A61P 25/04 (2006.01)
Patent
CA 2115792
A method of alleviating pain such as neuropathic pain or acute inflammatory pain is provided which comprises administering to a mammal that is either exhibiting pain or is about to be subjected to a pain-causing event a pain alleviating/pain suppressing amount of at least on a nontoxic antagonist for the N-methyl-D-aspartate receptor, e.g., dextrorphan, or metabolic precursor of such antagonist, e.g., dextromethorphan, or at least one nontoxic substance that blocks a major intracellular consequence of N-methyl-D- aspartate receptor activation, e.g., a phenothiazine such as trifluoperazine.
Lyle John W.
Mao Jianren
Mayer David J.
Price Donald D.
Mcfadden Fincham
Virginia Commonwealth University
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