A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/14 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) C07K 7/06 (2006.01) C07K 14/16 (2006.01)
Patent
CA 2172491
The present invention provides a method for the treatment or prevention of eczema/dermatitis. This method involves the administration of Peptide T or its derivatives or analogues. Preferred compounds used in the method include: 1) D-Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr-NH2; 2) Ala-Ser-thr-thr-Thr-Asn-Tyr-Thr; 3) D-Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr; 4) D-Ala-Ala-Ser-Ser-Asn-Tyr-Met; 5) Thr-Asp-Asn-Tyr-Thr; 6) Thr-Thr-Ser-Tyr-Thr; 7) Thr-Thr-Asn-Tyr-Thr; 8) D-Thr-Thr-Tyr-D-Thr; 9) D-Ala-Ser-D-Thr-Thr-D-Thr-Asn-Tyr-D-Thr-NH2; 10) D- Ser-Ser-D-Thr-Thr-D-Thr-Thr-Tyr-D-Thr-NH2.
L'invention qui porte sur le traitement ou la prévention de l'eczéma et des dermatites consiste à administrer un peptide T ou ses dérivés ou analogues. Les composés préférés utilisés présentent les séquences 1 à 10 suivantes: 1) D-Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr-NH2; 2) Ala-Ser-thr-thr-Thr-Asn-Tyr-Thr; 3) D-Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr; 4) D-Ala-Ala-Ser-Ser-Asn-Tyr-Met; 5) Thr-Asp-Asn-Tyr-Thr; 6) Thr-Thr-Ser-Tyr-Thr; 7) Thr-Thr-Asn-Tyr-Thr; 8) D-Thr-Thr-Tyr-D-Thr; 9) D-Ala-Ser-D-Thr-Thr-D-Thr-Asn-Tyr-D-Thr-NH2; 10) D-Ser-Ser-D-Thr-Thr-D-Thr-Thr-Tyr-D-Thr-NH2.
Michaelis Jurgen
Trigg Timothy Elliot
Advanced Immuni T. Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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