Method for transdifferentiation of non-pancreatic stem cells...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/00 (2006.01) A01N 37/18 (2006.01) A01N 63/00 (2006.01) C12N 5/02 (2006.01) A61K 35/12 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2442177

The subject invention comprises culture methods for transdifferentiation of non-pancreatic stem cells to the pancreatic differentiation pathway. It also concerns the endocrine hormones that can be produced by such cultures, and the use of the transdifferentiated cells in the treatment of pancreatic diseases.

L'invention concerne des procédés de culture destinés à la transdifférentiation de cellules souches non pancréatiques dans la voie de différentiation du pancréas. L'invention concerne également la production d'hormones d'endocrine par de telles cultures, ainsi que l'utilisation des cellules transdifférentiées dans le traitement de maladies du pancréas.

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