Method for transforming human b lymphocytes

Details Method for transforming human b lymphocytes Method for transforming human b lymphocytes

C - Chemistry, Metallurgy

12

N

195/1.102, 195/1

C12N 5/10 (2006.01) C12N 5/16 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2005744

28 ABSTRACT Disclosed herein is a method for transforming human B- cells preferably by infecting them with Epstein-Barr virus followed by transforming the Epstein Barr virus infected cells with an activated human ras gene. The transformed cells are useful for producing human monoclonal antibodies either without further manipulation or after fusion with antibody-secreting cells.

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