Method for treating a medical patient for cardiac trauma

A - Human Necessities – 61 – K

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A61K 31/19 (2006.01) A61K 31/195 (2006.01) A61K 31/22 (2006.01)

Patent

CA 2152487

A method for treating a medical patient prior to or during heart trauma, e.g., myocardial infarction, angina and ischemia. An effective dosage of pyruvate is introduced into the patient to increase the patient's cardiac output and stroke volume, to decrease the patient's heart rate and to reduce the oxygen demand of the patient's heart. The dosage may be introduced intravenously into the patient or orally as a component of the patient's diet. The oral feeding method is especially useful for surgical patients prior to surgical procedures which are likely to encourage cardiac trauma and useful for patients exhibiting symptoms of chronic congestive heart failure.

Procédé de traitement d'un patient avant ou pendant un traumatisme cardiaque tel que l'infarctus du myocarde, l'angine de poitrine et l'ischémie. Une dose efficace de pyruvate est administré au patient afin d'accroître son débit cardiaque et son volume systolique, de réduire sa fréquence cardiaque ainsi que les besoins en oxygène de son coeur. La dose peut être administrée au patient par voie intraveineuse ou oralement comme un constituant de son régime alimentaire. Le procédé d'administration par voie orale, dans l'alimentation du patient, convient particulièrement à des patients s'apprêtant à subir une intervention chirurgicale susceptible de favoriser un traumatisme cardiaque, ainsi qu'à des patients présentant des symptômes d'insuffisance cardiaque congestive chronique.

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