Method for treating bone fracture with anti-sclerostin...

Details Method for treating bone fracture with anti-sclerostin... Method for treating bone fracture with anti-sclerostin...

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61P 19/00 (2006.01) C07K 16/22 (2006.01)

Patent

CA 2707400

The invention provides a method of enhancing bone fracture healing involving administering a sclerostin inhibitor. In one aspect, the invention includes use of a therapeutically effective amount of sclerostin binding agent to treat a bone fracture, wherein one or more administrations of the sclerostin binding agent are administered over a treatment period lasting at least two weeks and beginning within two weeks of the fracture.

L'invention a pour objet un procédé d'amélioration de la guérison des fractures osseuses en administrant un inhibiteur de la sclérostine. Selon un aspect, l'invention implique l'utilisation d'une quantité thérapeutiquement efficace d'un agent de liaison de la sclérostine pour traiter une fracture osseuse. Une ou plusieurs administrations de l'agent de liaison de la sclérostine sont réalisées sur une période de traitement s'étendant sur au moins deux semaines et démarrant sous un délai de deux semaines à compter de la fracture.

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