Method for treating cancer using ahpn

Details Method for treating cancer using ahpn Method for treating cancer using ahpn

A - Human Necessities

61

K

A61K 38/19 (2006.01) A61K 31/19 (2006.01) A61K 31/192 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2223489

Methods for treating or preventing breast cancer or leukemia in subjects in need of such treatment are provided which involve the administration of 6-[3- [1-adamantyl]-4-hydroxyphenyl]-2-naphthalene carboxylic acid (AHPN), a retinoid which induces G0/G1 arrest and apoptosis. These methods are useful for treatment of breast cancers which express or do not express estrogen receptors.

Procédés de traitement ou de prévention du cancer du sein ou de la leucémie chez des sujets nécessitant un traitement, qui consistent à administrer de l'acide carboxylique de 6-[3-[1-adamantyl]-4-hydroxyphényl]-2-naphtalène, un rétinoïde qui induit l'arrêt G¿0?/G¿1? et l'apoptose. Lesdits procédés sont utiles pour le traitement des cancers du sein qui expriment ou n'expriment pas les récepteurs d'oestrogène.

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