Method for treating delirium

A - Human Necessities – 61 – K

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A61K 31/437 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2669463

Methods for treating delirium, including postoperative delirium, sepsis-associated delirium, and drug or alcohol withdrawal-associated delirium with ibudilast are disclosed. Treatment may further comprise administration of one or more other agents, such as analgesics, anti-inflammatory and central nervous system (CNS)-partitioning phosphodiesterase inhibitors, antidepressants, neuroleptics, benzodiazepines, and procholinergic agents.

L'invention porte sur des procédés permettant de traiter le délire, y compris le délire postopératoire, le délire lié à une sepsie et le délire lié au sevrage de drogue ou d'alcool, par l'ibudilast. Le traitement peut également inclure l'administration d'un ou plusieurs autres agents, tels que des analgésiques, des inhibiteurs de la phosphodiestérase anti-inflammatoires et de cloisonnement du système nerveux central, des antidépresseurs, des neuroleptiques, des benzodiazépines et des agents procholinergiques.

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