Method for treating diabetic vascular complications

A - Human Necessities – 61 – K

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A61K 36/8945 (2006.01) C07H 21/04 (2006.01)

Patent

CA 2656185

The present invention provides a method for treating diabetic vascular complications including administering to a subject in need thereof a therapeutically effective amount of an extract product of a Dioscorea species. The extract product preferably is prepared by a process which involves (a) extracting a tuber of the Dioscorea species with an alcohol-based solvent in the presence of an acetic acid solution to form an extract composition, (b) subjecting a resultant product obtained in step (a) to obtain a soluble fraction, and (c) removing solvent from the soluble fraction obtained in step (b) to obtain the extract product.

La présente invention concerne une méthode de traitement de complications vasculaires diabétiques qui comprend l'administration à un sujet le nécessitant d'une quantité thérapeutiquement active d'un produit extrait d'un membre de l'espèce Dioscorea. Le produit extrait est préférentiellement élaboré par un procédé qui implique (a) l'extraction depuis un tubercule de l'espèce Dioscorea à l'aide d'un solvant à base d'alcool en présence d'une solution d'acide acétique pour former une préparation d'extrait, (b) la soumission d'un produit résultant obtenu dans l'étape (a) pour obtenir une fraction soluble, et (c) l'élimination du solvant de la fraction soluble obtenue dans l'étape (b) pour obtenir le produit extrait.

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