Method for treating headache pain with topical local...

Details Method for treating headache pain with topical local... Method for treating headache pain with topical local...

A - Human Necessities

61

K

A61K 31/445 (2006.01) A61K 9/06 (2006.01) A61K 31/24 (2006.01) A61K 31/245 (2006.01) A61K 45/00 (2006.01) A61K 45/08 (2006.01) A61K 47/18 (2006.01) A61K 47/22 (2006.01) A61P 25/04 (2006.01) A61P 25/06 (2006.01)

Patent

CA 2283929

Methods are provided for the treatment of a host suffering from headache pain with topical applications of a local anesthetic. The topical local anesthetic composition comprises an effective amount of a local anesthetic in combination with eucalyptol as a penetration enhancing agent, and optionally an additional penetration enhancing agent. The topical local anesthetic composition is applied to a keratinized skin site proximal to target nerves associated with the headache pain, usually to the supraorbital or occipital regions of the head. Upon application of the topical composition, the local anesthetic rapidly penetrates the skin to block conduction in the target nerves and provide pain relief to the host.

L'invention concerne des procédés permettant de traiter une personne souffrant d'un mal de tête par applications topiques d'un anesthésique local. La composition d'anesthésique topique comprend une quantité efficace d'un anesthésique local combiné avec de l'eucalyptol, en tant qu'agent favorisant la pénétration, et éventuellement avec un autre agent favorisant la pénétration. La composition anesthésique topique est appliquée sur une région de la peau kératinisée proche des nerfs cibles associés au mal de tête, en général proche des régions sus-orbitaire et occipitale. Lorsque l'on applique la composition topique, l'anesthésique local pénètre rapidement dans la peau pour bloquer la conduction dans les nerfs cibles et supprimer ainsi la douleur de la personne.

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