Method for treating hepatitis c virus infection in treatment...

A - Human Necessities – 61 – K

Patent

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A61K 38/21 (2006.01) A61K 31/70 (2006.01) A61K 31/7056 (2006.01)

Patent

CA 2461596

The present invention provides methods for treating individuals having a hepatitis C virus (HCV) infection, which individuals havefailed to respond to therapy with an IFN-.alpha. other than consensus interferon (CIFN), or who, following cessation of therapy withan IFN-.alpha. other than CIFN, have suffered relapse. The methods generally involve a treatment regimen comprising administering a first dosing regimen of CIFN, followed by a second dosing regimenof CIFN. Ribavirin is administered with at least the second dosing regimen.

La présente invention concerne des techniques de traitement de personnes atteintes d'une infection par le virus de l'hépatite C (VHC), ces patients n'ayant pas réagi à une thérapie associant un interféron .alpha. (IFN-.alpha.) différent de l'interféron de consensus (CIFN), ou qui, à la suite de la cessation d'une thérapie associant un IFN-.alpha. différent de l'interféron de consensus (CIFN), ont subit une rechute. Ces techniques consistent en général en un schéma posologique de traitement comprenant l'administration d'un premier schéma posologique de CIFN, suivie par un second schéma posologique de CIFN. On administre de la ribavirine au moins dans le second schéma posologique.

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