C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 327/34 (2006.01) A61K 31/185 (2006.01) A61K 31/195 (2006.01) A61K 31/265 (2006.01) A61K 31/40 (2006.01) A61K 31/70 (2006.01) C07C 403/22 (2006.01) C07D 207/16 (2006.01) C07D 209/20 (2006.01) C07D 233/64 (2006.01) C07H 15/226 (2006.01) C07K 5/06 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2164955
A method for the topical or systemic treatment of hyperkeratosis or disorders mediated by proteases that includes the administration of an effective amount of N-acetylcysteine or a pharmaceutically acceptable salt or derivative thereof, and preferably, a lipophilic thioester or thioether of N-acetyl cysteine. In an alternative embodiment, the invention is a method for the treatment of inflammatory conditions or conditions that benefit from immunosuppression that includes the administration of an effective amount of a lipophilic thioester or thioether of N-acetyl cysteine.
L'invention concerne un procédé de traitement local ou systémique de l'hyperkératose ou de troubles induits par des protéases, qui consiste à administrer une quantité efficace de N-acétylcystéine ou d'un sel pharmaceutiquement acceptable ou d'un dérivé de celui-ci, et de préférence, un thioester lipophile ou un thioéther de N-acétylcystéine. Dans une autre variante de réalisation, l'invention concerne un procédé de traitement d'états inflammatoires ou d'états pathologiques qui se développent à la faveur de l'immunosuppression. Ce procédé consiste à administrer une quantité efficace d'un thioesther lipophile ou d'un thioéther de N-acétylcystéine.
Arndt Kenneth A.
Galli Stephen J.
Mcaloon Maureen H.
Sharpe Richard J.
Arcturus Pharmaceutical Corporation
Swabey Ogilvy Renault
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