A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/20 (2006.01)
Patent
CA 2253312
A use is provided of a combination of IL-10 and a steroid for the manufacture of a medicament for the treatment or prevention of inflammatory disease, in particular septic shock and inflammatory conditions caused by auto-immune diseases, such as inflammatory bowel disease, rheumatoid arthritis, multiple sclerosis, uveitis, and psoriasis. Also provided are pharmaceutical compositions and kits comprising IL-10 plus at least one steroid, e.g., betamethasone or its derivatives.
L'invention concerne l'utilisation d'une association d'IL-10 et d'un stéroïde pour la fabrication d'un médicament destiné au traitement ou à la prévention de maladies inflammatoires, notamment du choc septique et des états inflammatoires dus à des maladies auto-immunes, telles les maladies inflammatoires intestinales, la polyarthrite rhumatoïde, la sclérose en plaques, l'uvéite et le psoriasis. Elle concerne également des compositions pharmaceutiques et des matériels contenant de l'IL-10 et au moins un stéroïde, bétaméthasone ou ses dérivés, par exemple.
Narula Satwant K.
Smith Sidney R.
Ogilvy Renault
Schering Corporation
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