Method for treating inflammation using anti-idiotypic...

C - Chemistry – Metallurgy – 12 – P

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C12P 21/08 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01) C07K 16/42 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2092801

2092801 9206119 PCTABS00011 A method for inhibiting ICAM-1 dependent inflammatory responses by immunizing a patient with anti-ICAM-1 anti-idiotype antibodies or fragments thereof. Anti-ICAM-1 anti-idiotypic antibodies are also disclosed whose antigen combining site binds to an idiotype of an anti-ICAM-1 antibody that inhibits binding of ICAM-1 to an ICAM-1 leukocyte receptor.

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