Method for treating joint damage

Details Method for treating joint damage Method for treating joint damage

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 31/00 (2006.01) A61P 19/02 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2627886

Methods of treating joint damage in a subject eligible for treatment are provided involving administering an antagonist that binds to a B-cell surface marker, such as CD20 antibody, to the subject in an amount effective to slow progression of the joint damage as measured by radiography. Further provided are articles of manufacture useful for such methods.

La présente invention concerne des procédés destinés à traiter une lésion articulaire chez un sujet éligible pour le traitement, impliquant l'administration au sujet d'un antagoniste qui se lie à un marqueur de surface d'un lymphocyte B, tel qu'un anticorps CD20, en une quantité efficace en vue de ralentir la progression de la lésion articulaire, telle qu'elle est mesurée par radiographie. L'invention concerne en outre des produits de fabrication utiles pour de tels procédés.

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