Method for treating nervous system disorders and conditions

Details Method for treating nervous system disorders and conditions Method for treating nervous system disorders and conditions

A - Human Necessities

61

K

A61K 31/403 (2006.01) A61P 25/00 (2006.01) A61P 25/18 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2574310

The present invention is directed to racemic 1-(3,4-dichlorophenyl)-3- azabicyclo[3.1.0]hexane, (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.O]hexane, racemic 1-(4-methylphenyl)-3-azabicyclo[3.1.0]hexane, and (+)-1-(4- methyiphenyl)~-3-azabicyclo[3.1.0]hexane, and methods of their use for treating certain nervous system disorders and conditions, including, inter aliavasomotor symptoms (VMS) and chronic pain.

L'invention concerne les produits suivants : 1-(3,4-dichlorophényle)-3-azabicyclo[3.1.0]hexane racémique, (+)-1-(3,4-dichlorophényle)-3-azabicyclo[3.1.O]hexane, 1-(4-méthylphényle)-3-azabicyclo[3.1.0]hexane racémique, et (+)-1-(4-méthylphényle)--3-azabicyclo[3.1.0]hexane. Elle concerne aussi des procédés d'utilisation correspondants pour le traitement d'un certain nombre de troubles et affections du système nerveux, y compris, entre autres, les symptômes vasomoteurs et la douleur chronique.

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