Method for treating nervous system disorders and conditions

Details Method for treating nervous system disorders and conditions Method for treating nervous system disorders and conditions

A - Human Necessities

61

K

A61K 31/403 (2006.01) A61P 25/00 (2006.01) A61P 25/18 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2574420

The present invention is directed to racemic 1-(3,4-dichlorophenyl)- 3~azabicyclo[3.1.0]hexane, (+)-1-(3,4-dichlorophenyl)-3- azabicyclo[3.1.0]hexane, racemic 1-(4-methylphenyl)-3-azabicyclo[3.1.0]hexane, and (+)-1-(4-methylphenyl)~3-azabicyclo[3.1.0]hexane, and methods of their use for treating certain nervous system disorders and conditions, including, inter alia, vasomotor symptoms (VMS) and chronic pain.

La présente convention concerne 1-(3,4-dichlorophényle)-3-azabicyclo[3.1.0]hexane, (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane racémique, 1-(4-méthylphényl)-3-azabicyclo[3.1.0]hexane racémique, et (+)-1-(4-méthylphényle)-3-azabicyclo[3.1.0]hexane racémique, et des procédés d'utilisation de ces composés pour traiter certains troubles et certaines pathologies du système nerveux comprenant notamment, des symptômes vasomoteurs (VMS) et la douleur chronique.

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