Method for treating proliferative diseases by therapy

A - Human Necessities – 61 – K

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Details

A61K 51/00 (2006.01) A61K 51/12 (2006.01) C07B 59/00 (2006.01) C07C 251/38 (2006.01) C07C 323/32 (2006.01) C07F 13/00 (2006.01)

Patent

CA 2301887

The invention relates to a method for treating proliferative diseases by therapy, characterised in that an application catheter is first placed at the site of the lesion and a radioactive substance is applied locally. The catheter is then removed, leaving the radioactive substance at the site of the lesion. The invention also relates to the use of bis-amine-oxime derivative, N2S2 complex derivatives and radioactively marked colloidal solutions for producing agents which are applied locally in proliferative disease therapy.

L'invention concerne une méthode pour le traitement curatif des affections prolifératives, qui est caractérisée en ce qu'un cathéter d'application est tout d'abord placé au niveau du siège de la lésion et en ce qu'une substance radioactive est appliquée localement sur le cathéter, ce dernier est ensuite enlevé et la substance radioactive demeure au niveau du siège de la lésion. L'invention concerne également l'utilisation de dérivés de bisaminoxime, de dérivés complexes de N¿2?S¿2? et de solutions colloïdales radiomarquées pour la préparation d'agents qui sont appliqués localement lors du traitement des affections prolifératives.

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