Method for treating respiratory distress syndrome using leptin

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/19 (2006.01) A61K 38/22 (2006.01) C07K 14/52 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2428937

The invention provides a method for treating infants, children or adults suffering from pulmonary distress caused by low or insufficient production of surfactant. It is particularly suitable for treating premature infants suffering from Respiratory Distress Syndrome. The method comprises administering a leptin compound to an individual with impaired surfactant production for a time and in an amount sufficient to enhance surfactant production. The method may be used for treatment of any mammal with impaired lung surfactant production.

L'invention concerne un procédé servant à traiter des nouveau-nés, des enfants ou des adultes souffrant de détresse pulmonaire provoquée par une production basse ou insuffisante de tensioactifs. Ce procédé est particulièrement utile pour traiter des nouveau-nés prématurés souffrant du syndrome de la détresse respiratoire. Ce procédé consiste à administrer un composé de leptine à un individu dont la production de tensioactifs est déficiente, pendant une durée et en quantités suffisantes pour augmenter la production de tensioactifs. On peut mettre ce procédé en application afin de traiter tout mammifère dont la production de tensioactifs pulmonaires est déficiente.

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