A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/310
A61K 8/67 (2006.01) A61K 31/23 (2006.01) A61K 31/235 (2006.01) A61K 31/425 (2006.01) A61K 31/44 (2006.01)
Patent
CA 2035459
2035459 9101128 PCTABS00003 The effects of photoaging or sun damage of skin including loss of collagen fibers and deterioration of small blood vessels in the dermis of the skin are repaired by applying topically to the epidermis effective amounts of a compound having structure (I), wherein R1, R2, R3, R4 and R5 are independently selected from the group consisting of H, Cl, OR6, straight or branched alkyl of 1 to 10 carbon atoms, NO2, COOR6, CN, OR6, NR6R7, NR6C(=S)NR7R8, NR6COR7, SO2NR6R7, CH(CH3)COOH, CONR6R7, COR6, OCONR6R7, NR6COONR7, R9OR6, NR6SO2R7, Si(CH3)3, and NR6CONR7R8, R3 together with R4 forms a benzo ring or taken together with R2 forms a benzo or tetrahydrobenzo ring or together with R2 and R1 forms a (1) moiety or together with R2 forms a (2) moiety or R2 together with R1 forms a benzo ring or R2 together with R3 forms a (3) or (4) or (5) or (6) moiety, or R1 is independently selected from the group consisting of (7), (8) moiety, R6, R7 and R8 are independently selected from the group consisting of straight or branched alkyl containing from 1 to 10 carbon atoms, aryl containing from 6 to 10 carbon atoms and hydrogen, and R9 is alkylene of 1 to 6 carbon atoms, and iron carbonyl complexes thereof, to an area of the skin in an amount sufficient to repair the effects of elastosis in the skin. Lines and wrinkles due to aging are reduced and prevented.
Gendimenico Gerard J.
Haley Neil F.
Nair Xina
Eastman Kodak Company
Gendimenico Gerard J.
Gowling Lafleur Henderson Llp
Haley Neil F.
Nair Xina
LandOfFree
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