Method for treatment of angiogenic disorders

Details Method for treatment of angiogenic disorders Method for treatment of angiogenic disorders

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 31/711 (2006.01) A61K 31/713 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2520518

A therapeutic method for treatment of non-cancerous angiogenesis-related diseases involves administering a therapeutically effective amount of a composition effective to reduce the effective amount of clusterin in the individual. Preferred therapeutic compositions contain antisense oligonucleotides which reduce the effective amount of clusterin.

L'invention concerne une nouvelle méthode pour traiter les maladies non cancéreuses liées à l'angiogenèse, consistant à administrer une quantité efficace sur le plan thérapeutique d'une composition réduisant efficacement le taux effectif de clusterine chez un individu. Des compositions thérapeutiques préférées contiennent des oligonucléotides antisens qui réduisent le taux effectif de clusterine.

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