A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 36/47 (2006.01) A61K 36/38 (2006.01) A61P 1/12 (2006.01) A61K 31/353 (2006.01)
Patent
CA 2650294
The present invention provides methods for treating diarrhea-predominant irritable bowel syndrome comprising administering to a patient in need thereof, an inhibitor of chloride-ion transport in an amount sufficient to treat diarrhea-predominant irritable bowel syndrome (d-IBS). Treatment of d-IBS includes the treatment of the diarrhea component of d-IBS as well as the pain, abdominal discomfort and other symptoms associated with d-IBS. In one embodiment, the inhibitor of chloride-ion transport is crofelemer.
L'invention concerne des méthodes permettant de traiter le syndrome du côlon irritable à diarrhée prédominante, qui consistent à administrer à un patient nécessitant un tel traitement un inhibiteur de transport d'ions chlorure à une dose suffisante pour traiter le syndrome du côlon irritable à diarrhée prédominante (d-IBS). Le traitement du d-IBS consiste à traiter la diarrhée associée au d-IBS ainsi que la douleur, la gêne abdominale et d'autres symptômes associés au d-IBS. Dans un mode de réalisation, l'inhibiteur de transport d'ions chlorure est le crofelemer.
Blanks Robert
Neenan Thomas
Quart Barry
Rosenbaum David
Gowling Lafleur Henderson Llp
Napo Pharmaceuticals Inc.
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